About Us
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| Professor T.W. Swerczek |
Professor T.W. Swerczek, a veterinary pathologist at the
University of Kentucky had observed several years ago that the overuse of
antibiotics would lead to antibiotic resistant super bacterial infections.
Currently, there are bacteria and fungi that are resistant to nearly all
antibiotics. Dr. Swerczek was the first to isolate the Contagious Equine
Metritis (CEM) organism in the USA and showed that antibiotic resistant CEM
bacteria had developed. He used the bacterium as a model to study and develop
monosaccharide sugars, and their antibacterial derivatives as natural
alternatives to antibiotics for the prevention and treatment of bacterial and
fungal infections of the skin and reproductive tract.
While working on alternatives to antibiotics to treat resistant bacteria and
super-bacterial infections of the reproductive tract of horses, Dr. Swerczek
developed a solution for wound healing. He also observed several years ago
that many of the commonly used antibiotics and disinfectants would not only
induce resistance, but inhibited wound healing. Currently, in human medicine,
they are coming to the same conclusion, and now are recommending that wounds
should be washed with sterile water or saline and then kept dry for best wound
healing. Unfortunately, because of the emergence of resistant, super-bacterial
infections, like Staphylococcus, this is not always possible, and even more
potent antibiotics are necessary to threat these life-threatening infections
that may become systemic. Similarly, unlike humans, it is not possible to keep
animal wounds clean and dry as they are commonly exposed to opportunistic and
pathogenic organisms in the environment that contaminate wounds.
Dr. Swerczek’s son Timothy M. Swerczek, BS. JD. is president and CEO of Woundade
Inc. This company manufactures Woundade ™, and UterineAde™ |
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History of the Development of Woundade ™ and UterineAde™
Solutions. |
Woundade , like so many discoveries in science, was discovered by accident and
the reason why it works so dramatically to accelerate wound healing is still a
mystery.
The solution of sugars in UterineAde was originally developed to treat venereal
diseases of horses. The discovery that normal flora of the reproductive tract of
horses utilize monosaccharide sugars to produce sugar-derived metabolites, which
in turn inhibit pathogenic bacteria 1, is likely an important mechanism of
action. These natural antibacterial monosaccharide derivatives are the basis for
the development of UterineAde solutions
Since most wounds are infected with multiple opportunistic and pathogenic
bacteria, the solution was tested on traumatic wounds, many of which were
infected. The expected occurred in that the solution was highly effective in
inhibiting the proliferation of bacteria in the infected wounds. But, in
addition, the solution remarkablely accelerated all phases important for wound
healing, namely contraction of the fresh wound, vascularization and
epithelization. Also, the solutions prevented excessive granulation tissue,
scarring, and the hair grew back the same color at the wound site.
Since the wound healing properties of the solution were serendipitous, the
mechanism of action by which the solution accelerates wound healing is unknown.
The most logical explanation, Woundade and UterineAde solutions seemingly
provide nutrients for the body’s cellular structures and functions to naturally
inhibit pathogens and to promote wound healing by stimulating the epithelial and
mucosal cells to produce natural secretions and mucus.
Since it was obvious to equine practitioners that the novel solution induced
wound healing unlike any other therapies for wound healing in horses, there was
a great demand for the solution, especially for horses since their wounds are
more difficult to heal than other animals.
Currently, there is considerable interest in using mannose, a monosaccharide
sugar, as an aid for the treatment of urinary tract infections in humans and for
reproductive tract infections in mares.2 Woundade and UterineAde solutions are
broad spectrum in action as they not only contain the monosaccharide sugar,
mannose, but other monosaccharide sugars, natural mineralized sea salts, and
organic natural nutritional sodium salts.
Recent research has proven that that adequate sodium is essential for optimum
reproductive fertility. An increase in sodium in the cervico-vaginal mucus is
required during estrus for high conception rates. 3 A deficiency in sodium
increases infertility and embryonic mortality4,5 . Woundade and UterineAde
solutions contain natural sodium sea salts.
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or call 888-509-4220 |
References:
1. Swerczek, T.W.: Inhibition of the CEM organism by the Normal Flora of the
Reproductive Tract. Vet. Rec. 1978, 103:125.
2. King, S.S. et.al.: Use of specific sugars to inhibit bacterial adherence to
equine endometrium in vitro. AJVR. 2000, 61:446-449
3. Arya, S.P. and Jain, Y.C.: 1986. Sodium and potassium concentrations of
cervico-vaginal mucus in relation to oestrous cycle and early pregnancy
in Jersey cows. Indian Journal of Animal Science. 56:331.
4. Harris, D.J., Allen, J.D., and Caple, I.W.: 1986. Effects of low sodium
nutrition on fertility of dairy cows. Proceeding of the Nutritional Society of
Australia 11:92.
5. Cromwell, G.L., Hall, D.D. Combs, O.M. et.al.: 1989. Effects of dietary salt
level during gestation and lactation on reproductive performance of sows. A
cooperative study. J. Animal Science. 67:374.
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